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Mice lacking the Gpx4 allele in IECs show signs of epithelial LPO and focal neutrophilic enteritis with a granuloma-like accumulation of inflammatory cells when fed a PUFA-rich diet (65)

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It provides for better and more efficient delivery of the nutrient into the body

The study was performed by subjecting adjuvant-induced arthritis (AIA) rats to fractionated WBI (6 Gy of -rays: 2 Gy/fraction once per week for 3 consecutive weeks) and treating them with ebselen (20 mg/kg/day)